Tales to Astonish #27 (1962)

Doctor Henry Pym declares success! He has successfully used his reducing serum to shrink a chair to doll size and used his enlarging serum to return it to normal size. Pym had been ridiculed months ago by his peers for his outlandish theories but has now perfected a pair of serums capable of changing the size of any object. Confident that his serums work, Pym tests them on himself. Placing a few drops of reducing serum on his arm, Henry Pym quickly shrinks. Now ant-sized, he realizes that he left the enlarging serum on the window sill; it might as well be on the moon. He goes out into the yard. Ants sense his presence and move toward him. Pym, still not thinking clearly, runs into an ant hill. Fleeing blindly through the tunnels, he falls into a shaft and lands in a pool of honey. Hopelessly trapped, he spots an ant crawling towards him. To Pym’s surprise, the ant pulls him free from the honey and lets him go unharmed. More ants appear. Pym notices a matchstick set in the ground and, hoping to create a diversion, throws a pebble at it. His aim is true, and the match lights. Pym fashions a lasso and climbs up to a ledge. There, another ant grabs him in its mandibles. Pym uses judo to flip the ant over the ledge and scrambles upward. Once out of the ant hill, with the colony in hot pursuit, he sees the friendly ant who saved him earlier. He points upward to tell the ant where he needs to go. The ant climbs the wall with Pym aboard. He wades into the test tube with the serum and immediately returns to normal. Convinced that his invention is dangerous, he dumps his serums down the drain.